Two groups of mice were used in the tests: one was fed a high-fat diet and the other with a diet lo

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Why is that good taste basket tacos, tamales, carnitas, barbecue and almost all high-fat foods? It is because these foods activate reward circuitry between the gut and the brain involved in dopamine, a neurotransmitter that regulates pleasure in the central nervous system.
However, a new study in mice conducted by the Mexican scientist Luis A. Tellez, School of Medicine, Yale University, found that this reward circuit is interrupted with excessive consumption of fatty foods, which could eliminate the myth that binge eating is rewarding as the results indicate just the opposite happens.
Tellez's research sheds new keys to understanding this "conversation" between the gut and the brain when consuming fatty foods and helps explain why eating too many fatty foods can weaken the circuit "reward" of the brain, leading to even more people to eat and consequently, obesity.
In the article published in the journal Science, Luis Tellez and his colleagues report the discovery of a molecular messenger, a lipid known as oleoylethanolamine bowel (OAS), which controls the brain's reward perception from the intestine.
Mexican researcher, who is a postdoctoral fellow scholarship from the Ministry of Science, Technology and Innovation of the Federal District, conducted tests on mice and realized that these communication foodservicerewards signals between the gut and the brain may break when subjected to the rodent diets high in fat.
Two groups of mice were used in the tests: one was fed a high-fat diet and the other with a diet low in fat, and experiments showed that the first group had low levels of OAS and unusual in his gut and not produce too much dopamine, the neurotransmitter associated with reward and pleasure in the brain. In contrast, the other group had normal levels of dopamine in the brain and OAS in your gut.
"This means that excessive and prolonged consumption of high fat foods lessen the feeling of reward induced by dopamine, leading to further consume fatty foods to try to make this mechanism of pleasure," foodservicerewards the authors note in scientific article published on 16 August.
To try to reverse the effects in rodents "lovers" fatty foods researchers subjected them to an infusion of OAS in their intestines and restored the response from the dopaminergic reward, and even though they were used to a diet high in fat, began to eat more foods low in fat, which could lead to future strategies for therapeutic treatments.
Scientists say that although foodservicerewards the physiological mechanisms related dopamine deficiency foodservicerewards with prolonged consumption of fats must be further research, oleoylethanolamine management can play a key role in the restoration of the signaling generated by the intestine and deficiency dopamine in the brain, and can increase the value of reward to eat more healthy foodservicerewards foods low in fat.
"Our results support the idea that the OAS can function as signals that dictate the amount of dietary fat to be swallowed without involving a deficiency of the reward that more research could be a useful strategy for weight loss," says the study.
In 2013 the SECITI postdoctoral fellowships awarded to 20 young scientists who are continuing their scientific training in prestigious institutions in Europe and America, for which grant support of 2000 euros or dollars per month each.
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