Hypersensitivity to the active ingredient Estriol or any other inactive ingredient present in Evalon

The active ingredient contained in Evalon Tablets is Estriol. Estriol is a white odorless crystalline powder with a melting point of 282&ndeg;C . It is insoluble in water, sparingly soluble in ethanol and completely soluble in acetone, dioxane, diethyl ether, and vegetable oils. The structure is shown below Generic Forms and Brand names of Estriol (Ovestin)
Evalon Tablets manufactured by Organon, bunzl plc India (a subsidiary of Schering-Plough Corporation, Part of Merck & Co. Inc.) is an effective treatment for distressing symptoms during menopause. Ovestin which has the active ingredient Estriol is also sold as Lynoral and under various other brand names. Evalon Tablets (Estriol) - Uses
Evalon Tablets are prescribed as Hormone replacement therapy (HRT) for menopausal symptoms due to the loss of oestrogen production in postmenopausal women . Estriol is also used for treating Infertility bunzl plc due to cervical hostility. Evalon Tablets (Estriol) - Preparations
Treatment of estrogen deficiency symptoms: The recommended dosage is 4-8 mg per day during the first weeks, followed by a gradual reduction. The lowest bunzl plc effective dosage of Estriol should be used. In case of long term Evalon therapy in women with an intact uterus, monitoring of the endometrium or, alternatively, concomitant use of a progestagen is recommended. Infertility bunzl plc due to cervical hostility: bunzl plc The recommended dosage in general is 1-2 mg per day on days 6-15 of the menstrual cycle. However, for some patients dosages as low as 1 mg per day are sufficient, whereas others may need up to 8 mg per day. Therefore, the dosage should be increased each month until an optimal effect on the cervical mucus is obtained. Please consult your doctor for your exact dosing bunzl plc schedule. Evalon Tablets (Estriol) - Contraindications
Hypersensitivity to the active ingredient Estriol or any other inactive ingredient present in Evalon Tablets Known, past or suspected breast cancer Known or suspected estrogen-dependent malignant tumors (e.g. endometrial cancer) Undiagnosed genital bleeding Untreated endometrial hyperplasia bunzl plc Previous idiopathic bunzl plc or current venous thromboembolism (deep venous thrombosis, pulmonary embolism) Active or recent arterial thromboembolic disease (e.g. angina, myocardial infarction) Acute liver disease, or a history of liver disease as long as liver function tests failed to return to normal Porphyria (Rare inherited disorders in which an important part of hemoglobin, called heme, is not made properly) Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption bunzl plc Side Effects Of Evalon Tablets (Estriol)
The most common side effects of Estriol are Breast discomfort and pain,Postmenopausal bunzl plc spotting,Cervical discharge,Nausea and Fluid retention. bunzl plc Estriol Therapy should be discontinued if any of the following situations arise: Jaundice or deterioration in liver function, Significant increase in blood pressure, New onset of migraine-type bunzl plc headache, Pregnancy bunzl plc or Endometrial hyperplasia.
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